Vitamin D3 Supplementation for patients with type 2 diabetes. Clinical study

Abstract

Objective Type 2 diabetes (T2D) is characterized by insulin resistance and elevated blood glucose levels. Recent studies suggest that vitamin D3 might influence glucose metabolism and insulin sensitivity. This study aimed to evaluate the impact of vitamin D3 supplementation on hemoglobin A1c (HbA1c) and glucose levels in patients with type 2 diabetes. Materials and Methods This case-control study was conducted at Dr. Benzerjeb Hospital in Ain Temouchent and included adult patients with type 2 diabetes from February 18, 2024, to June 6, 2024. Patients' HbA1c and glucose levels were measured before and after oral vitamin D3 supplementation, with dosage adjustments based on initial vitamin D levels. Results The results showed a significant reduction in HbA1c, decreasing from 8,74% ± 1.40 to 8,51% ± 1.02 in patients. Glucose levels also showed a slight decrease, from 1,64 ± 0.46 g/L to 1,63 ± 0.59 g/L Conclusion The study revealed a high prevalence of hypovitaminosis D in the studied population, highlighting a potential need for supplementation.