Étude in vitro des activités biologiques des extraits des écorces d'oranges

Abstract

Industries generate a large amount of waste such as orange peels. They are an important source of secondary metabolites, the peel is the part where methanolic, ethanolic extracts are found in large quantities they have beneficial effects on human health because they possess many biological activities. In this perspective we have evaluated the biological activities of the ethanolic and methanolic extracts. Our results showed a significant cytotoxicity of our methanolic and ethanolic extracts at high concentrations, moreover the results of this present work demonstrate that the ethanolic and methanolic extracts have considerable anti-hemolytic effects compared to the reference molecules tested, the ethanolic and methanolic extracts also revealed an effective inhibition of the thermal denaturation of bovine albumin with maximum percentages of methanol extract at 86%, ethanol at 96% and 99.18% of diclofenac Our work therefore allows us to conclude that the extracts of orange peels have effects that provide antiinflammatory and anti-hemolytic activities at well determined concentrations.