L’effet antibactérien de la vitamine C chez les souches responsables des infections buccales

Abstract

Oral health is closely linked to overall well-being and represents a major public health concern. In response to the increasing bacterial resistance to antibiotics, interest in natural alternatives such as vitamin C has been steadily growing. Known for its antioxidant properties, vitamin C also shows promising antibacterial activity against various infections. In this context, the present study aimed to isolate strains responsible for oral infections in order to evaluate the antibacterial effect of vitamin C. The in vitro antibacterial activity of different concentrations of vitamin C in solution was examined, using a bioactivity-guided approach, against staphylococci and enterobacteria isolated from oral infections. The tests carried out showed that some strains were sensitive to vitamin C. The effect of various concentrations of ascorbic acid on bacterial growth was specifically studied in Acinetobacter baumannii, Pseudomonas putida, Pseudomonas aeruginosa, Escherichia coli, and staphylococci, revealing a real antibacterial activity.