Préparation et Identification de Nouveaux Hétérocycles

Abstract

Pyridones are a class of pharmacophores that exhibit important biological activities. Their structures have attracted much attention due to their uses as intermediates for the synthesis of a wide range of heterocyclic compounds and as starting materials for drug synthesis. The objective of our internship was the development of novel synthetic routes for 2-pyridones and their application for the environmentally friendly production of pyrazolo(3,4-b)pyridine. Relatively simple and efficient synthetic routes were used to access new fluorophores, studies were conducted to determine their physico-chemical properties as well as the effect of concentration on the molecular fluorescence intensity of 2-pyridone derivatives (PYF06, PYF07, PYF08) in chloroform (CHCl3) at different concentrations 10-4 ,10-5 and 10-6 M