Synthèse et évaluation des propriétés fluorescentes des dérivés chroménopyridines

Abstract

Heterocycles constitute the basic architecture of many natural or synthetic biological compounds. Recently, the latter have attracted a lot of attention from organic chemists because of their different biological activities and their various applications in organic synthesis. In this context our work is situated, and it is divided into two parts:  In the first part of this work, we succeeded in developing a new simple, effective, original synthetic route which gives good yields for the preparation of new nitro genous heterocycles derived from chromenopyridines: 7-amino-6 -oxo-6H-benzo[c]chromene-8-carbonitriles from 4-methyl-2-oxo-2Hchromene-3-carbonitrile and arylacrylonitriles (the alkenes).  The second objective of our work is devoted to the study of the molecular fluorescence of 7-amino-6-oxo- 6H-benzo[c]chromene-8-carbonitriles and 4-methyl-2-oxo-2H-chromene-3-carbonitrile (starting material) in different solvents and at different concentrations.