Evaluation de l’activité anti inflammatoire de l’extrait enrichi en polyphénols de Marrubium vulgare L.

Abstract

The aim of the present study is to evaluate the inflammatory activity of butanolic extract of the aerial part of Marrubium vulgare, a plant of the Lamiaceae family, widely used in traditional medicine for the treatment of a variety of diseases. Determination of total phenols by Folin-Ciocalteu method and flavonoids by aluminum trichloride (AlCl3) and sodium nitrite (NaNO2) method to butanolic extract gave values of 142 ± 2.66 mg EAG/g extract and 288, 53 ±19.88 mg EC/g extract respectively. The study of the anti-inflammatory activity in vitro of the butanolic extract of Marrubium vulgare shows that this extract has a very important percentage of inhibition of the hemolysis caused by heat and even by the hypotonic solution, and therefore a protective activity of the red blood cells.