Hadjoudja KheiraMeryem ABI-AYAD2026-09-292026-09-292026https://dspace.univ-temouchent.edu.dz/handle/123456789/7694This work aims to evaluate the impact of a combined vitamin D3 and chromium supplementation in patients with type 2 diabetes. The study consisted of assessing and comparing two key metabolic biomarkers — fasting glucose and glycated hemoglobin (HbA1c) — before and after the supplementation period. The results revealed an improvement in glycemic parameters among the monitored patients. Indeed, the mean fasting glucose decreased from 1.37±0.53 g/L (among 14 patients evaluated before the intervention) to 1.14 ± 0.35 g/L (among 10 patients evaluated after the supplementation). Furthermore, a notable reduction in the mean HbA1c was recorded, dropping from 7.17± 1.71 % to 6.33 ± 1.44 %. These data suggest a favorable and beneficial effect of vitamin D3 and chromium supplementation on glycemic control in type 2 diabetic patients, although postsupplementation HbA1c values remain close to the prediabetes zone according to the ADA criteria.frType 2 diabetes – Vitamin D3 – Chromium – Supplementation – Fasting glucose – HbA1c.Thesis